The superior clinical outcome of new continuous flow left ventricular assist devices
(LVAD) compared with pulsatile devices challenges the physiological dogma that cardiovascular
autonomic regulation requires pulsatile blood flow and pressure. We hypothesized that
continuous flow LVAD impairs baroreflex regulation of heart rate (HR) and sympathetic
nerve traffic (MSNA).
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© 2010 Published by Elsevier Inc.