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Physical exercise is an adjuvant treatment to control and prevent cardiovascular dysfunction
which results in the reduction of the occurrence of complications and mortality. A
reduction in baroreflex sensitivity is related to autonomic dysfunction and increases
mortality risk in cardiac patients. Therefore we aimed to evaluate changes in baroreflex
function in response to low intensity resistance training in rats. The animals were
enrolled in the trained group (TG, n=5) or sedentary group (SG, n=5). The exercise was performed on a squat-training apparatus using 3×10 repetitions, 3 times a week for 8 weeks. The SG was placed on the squat-training apparatus but performed no exercise.
After measurement of the maximum weight lifted (1RM), the training load was set at
40% of 1RM and adjusted every 15 days. At the end of the training protocol or time control, the animals were anesthetized
with thiopental (50 mg/kg i.p.) and are instrumentated to record blood pressure (BP) and analyze spontaneous
baroreflex sensitivity (BRS). There was a decrease in the heart rate (TG=365.4±7.796; SG=405.0±4.492; p=0.0023) and increase in BRS (TG=0.8809±0.01026; SG=0.8088±0.01882; p=0.0099) in trained animals when compared to sedentary, without changes in blood pressure
between groups. The low intensity resistance training was able to promote an increase
in spontaneous baroreflex sensitivity and therefore bradycardia in trained animals.
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