Purinoceptors are widely expressed in most tissues, including the rat urinary bladder, and are well known to possess both pro- and anti-inflammatory functions. Muscarinic receptors are the main contractile receptors in the rat urinary bladder. In the current study, we investigated the impact of pre-treatment with purinergic antagonists on the cholinergic contractile function of the rat urinary bladder during inflammation.
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© 2010 Published by Elsevier Inc.