Background: Interstitial cystitis (IC — Bladder Pain Syndrome), is characterized by pain in the
bladder worse when full and better when empty along with urgency and frequency. Despite
extensive research, the pathophysiology is unknown and there is no effective treatment.
ICEPAC aims to evaluate psychophysiologic contributions to this disorder, and to determine
whether this stress response demonstrates similar abnormalities to one of the animal
models.
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© 2010 Published by Elsevier Inc.