Design and feasibility of ICEPAC (Interstitial Cystitis Elucidation of Psychophysiologic and Autonomic Characteristics) — Bupivacaine instillation and urodynamic measures

      Background: Interstitial cystitis (IC — Bladder Pain Syndrome), is characterized by pain in the bladder worse when full and better when empty along with urgency and frequency. Cross organ sensitization in pelvis complicates the clinical diagnosis and treatment of IC/PBS as part of general chronic pelvic pain (CPP). ICEPAC aims to assess the signature of pain and voiding dynamic changes in response to peripheral afferent nociceptor block by local anesthetic.
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