Background: Interstitial cystitis (IC — Bladder Pain Syndrome), is characterized by pain in the
bladder worse when full and better when empty along with urgency and frequency. Cross
organ sensitization in pelvis complicates the clinical diagnosis and treatment of
IC/PBS as part of general chronic pelvic pain (CPP). ICEPAC aims to assess the signature
of pain and voiding dynamic changes in response to peripheral afferent nociceptor
block by local anesthetic.
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© 2010 Published by Elsevier Inc.
