Background: Anxiodepressive symptoms were associated with a significantly higher risk of fatal cardiovascular events. This appear to be attributable largely to an increase in sudden cardiac death, predicted by high sympathetic activity and decrease in heart rate variability. However, the central mechanism involved in this pathological alteration remained unknown. The dorsal medial nucleus of the hypothalamus (DMH) is part of acute arousal responses in stress (defense) situation, and its stimulation induces an increase in sympathetic activity. Our aim was to study the possible role of the DMH in the sympathetic alterations in chronic stress.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Autonomic Neuroscience: Basic and Clinical
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
© 2010 Published by Elsevier Inc.