Background: Local synapses within medial prefrontal cortex (MPFC) modulate the baroreflex. This action is mediated, at least in part, by NMDA receptors present in this area. Cannabinoid CB1 receptor expression is considerably high in MPFC. Also, these receptors can modulate postsynaptic response mediated by glutamatergic NMDA receptors.
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© 2010 Published by Elsevier Inc.