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Background: Local synapses within medial prefrontal cortex (MPFC) modulate the baroreflex. This
action is mediated, at least in part, by NMDA receptors present in this area. Cannabinoid
CB1 receptor expression is considerably high in MPFC. Also, these receptors can modulate
postsynaptic response mediated by glutamatergic NMDA receptors.
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