Background/aims: Dorsomedial hypothalamus (DMH) and lateral / dorsolateral periaqueductal gray (PAG)
are anatomically and functionally connected. Both DMH and PAG depend on glutamatergic
inputs to be activated. We recently reported that removal of GABAergic tone in unilateral
DMH produces: asymmetry – right sided predominance in cardiac chronotropism; lateralization – greater increases in ipsilateral renal sympathetic activity. This study investigated
the role of the excitatory amino acids (EAA) of the DMH and PAG in the functional
interhemispheric difference reported previously.
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© 2010 Published by Elsevier Inc.
