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Influence of sequential breathing on heart rate variability tests of cardiovagal function

      Two popular tests of cardiovagal function that measure the heart rate response to deep breathing are the mean heart rate range (MHRR) and the expiratory to inspiratory ratio (E:I). The MHRR utilizes 6 sequential deep breaths to calculate a mean heart rate range, mean of the maximum minus the minimum heart rate for each breath. The E:I is calculated from a single deep breath (maximum/minimum heart rate), assuming that the first deep breath will provide the maximum ratio.
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