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Does the dorsal motor nucleus of the vagus control cardiac chronotropism in the rat?

      Both the nucleus ambiguus (NA) and dorsal motor nucleus of the vagus (DMV) contain vagal preganglionic neurons with projections to the cardiac vagal ganglia. While NA cardiac vagal preganglionics exert a strong cardio-inhibitory influence on heart rate, it is unclear whether DMV preganglionics have the same role. We used a viral vector-mediated optogenetic strategy to investigate the relative influence of NA and DMV neurons on cardiac chronotropy.
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