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Evidence for neuroepithelial bodies (NEBs) as vagal mechanotransducers in the intrapulmonary mouse airway epithelium

      NEBs are morphologically well-defined airway receptors composed of densely innervated groups of neuroendocrine cells shielded from the airway lumen by Clara-like cells, together composing the NEB microenvironment. Because NEBs are contacted by at least two different populations of myelinated vagal afferents with intraepithelial nerve terminals, it seems likely that NEBs are the morphological counterparts of at least a subpopulation of the electrophysiologically characterized vagal mechanosensory airway receptors.
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