Highlights in basic autonomic neurosciences: The vagus and the ventricles

      The whole hearts of neonatal lambs were subjected to histochemical detection of vagal nerve fibres and ganglia. The methods included demonstration of acetylcholinesterase (AChE) activity as a marker of cholinergic nerves and immunohistochemistry of tyrosine hydroxylase (TH) an enzyme associated with bioaminergic fibres. The results showed an abundance of epicardial ganglia distributed widely along ovine ventricular nerves for some distance below the coronary groove. None of the ACHE positive ganglia were positive for TH.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Autonomic Neuroscience: Basic and Clinical
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Dobrzycki S.
        • Baniukiewicz A.
        • Korecki J.
        • Bachórzewska-Gajewska H.
        • Prokopczuk P.
        • Musial W.J.
        • Kamiński K.A.
        • Dabrowski A.
        Does gastro-esophageal reflux provoke the myocardial ischemia in patients with CAD?.
        Int. J. Cardiol. 2005; 104: 67-72
        • Hoover D.B.
        • Neely D.A.
        Differentiation of muscarinic receptors mediating negative chronotropic and vasoconstrictor responses to acetylcholine in isolated rat hearts.
        J. Pharmacol. Exp. Ther. 1997; 282: 1337-1344
        • Jones J.F.X.
        Vagal control of the rat heart.
        Exp. Physiol. 2001; 86 (Nov): 797-801
        • Rysevaite K.
        • Saburkina I.
        • Pauziene N.
        • Vaitkevicius R.
        • Noujaim S.F.
        • Jalife J.
        • Pauza D.H.
        Immunohistochemical characterization of the intrinsic cardiac neural plexus in whole-mount mouse heart preparations.
        Heart Rhythm. 2011; 8 (May): 731-738
        • Woolley D.C.
        • McWilliam P.N.
        • Ford T.W.
        • Clarke R.W.
        The effect of selective electrical stimulation of non-myelinated vagal fibres on heart rate in the rabbit.
        J. Auton. Nerv. Syst. 1987; 21: 215-221