Background: Intermittent hypoxia causes a persistent increase in sympathetic activity, which progresses to hypertension in chronic conditions such as obstructive sleep apnoea. Pituitary adenylate cyclase activating polypeptide (PACAP) is an excitatory neurotransmitter with long-lasting sympathetic effects.
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Received: May 15, 2013
© 2013 Published by Elsevier Inc.