PACAP causes the long-term increase in sympathetic activity evoked by acute intermittent hypoxia

      Background: Intermittent hypoxia causes a persistent increase in sympathetic activity, which progresses to hypertension in chronic conditions such as obstructive sleep apnoea. Pituitary adenylate cyclase activating polypeptide (PACAP) is an excitatory neurotransmitter with long-lasting sympathetic effects.
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