Autonomic neuropathy is a common complication of diabetes mellitus, but impairment
of sympathetic innervation appears differently in different vascular beds. According
our data, intermediate-stage (6-week) diabetes reduces the density of periarterial
nerve plexus in small renal arteries by 30%. The aim of this study was to test the
hypothesis that such partial denervation affects adrenosensitivity of renal arteries
from diabetic rats and to explore the possible mechanisms.
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Article info
Publication history
Received:
May 15,
2013
Identification
Copyright
© 2013 Published by Elsevier Inc.
