Abstract| Volume 177, ISSUE 1, P47-48, August 2013

Neurogenesis in Sympathetic Ganglia: Expression and Function of Prox1

      Neurogenesis in sympathetic ganglia is exceptional as initial neuroblast generation from neuron precursor cells is followed by neuroblast proliferation, which produces the majority of postmitotic sympathetic neurons during this second phase of neurogenesis. Prox1 is a homeodomain transcription factor with essential functions in neuron differentiation, maturation and progenitor survival, but its role during neurogenesis of the autonomic nervous system has not been investigated.
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