Neurogenesis in sympathetic ganglia is exceptional as initial neuroblast generation
from neuron precursor cells is followed by neuroblast proliferation, which produces
the majority of postmitotic sympathetic neurons during this second phase of neurogenesis.
Prox1 is a homeodomain transcription factor with essential functions in neuron differentiation,
maturation and progenitor survival, but its role during neurogenesis of the autonomic
nervous system has not been investigated.
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Publication history
Received:
May 15,
2013
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Copyright
© 2013 Published by Elsevier Inc.