If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. You will then receive an email that contains a secure link for resetting your password
If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password
Background: Although, it is usually difficult to differentiate multiple system atrophy
(MSA) from Parkinson’s disease (PD), we have previously reported that post-void residuals
and sphincter electromyography were useful for differentiation 1), 2). However, we did not know which is more appropriate in differentiating MSA from PD.
Aims: We aimed to perform receiver operating characteristic analysis to determine
the ability of sphincter electromyography (mean duration) and post-void residuals
(free flow study and pressure-flow study) for distinguishing multiple system atrophy
from Parkinson’s disease. Methods: We retrospectively reviewed 241 case records where
both urodynamic study and sphincter electromyography were performed in patients with
multiple system atrophy (n = 147) and Parkinson's disease (n = 94). We performed receiver operating characteristic analysis of the data sets. Results:
The area under the curve (AUC) used to differentiate multiple system atrophy from
Parkinson’s disease was 0.79 in post-void residuals during pressure flow study, 0.73
in post-void residuals during free-flow study and 0.69 in mean duration of sphincter
electromyography, respectively; these values were statistically significant. Conclusion:
The present results suggested that post-void residuals were more appropriate than
mean duration of sphincter electromyography in differentiating MSA from PD. In particular,
the AUC in post-void residuals under pressure flow study was larger than that of under
free-flow study. 1) Yamamoto T, Sakakibara R, Uchiyama T, Yamaguchi C, Ohno S, Nomura
F, Yanagisawa M, Hattori T, Kuwabara S. Time-dependent changes and gender differences
in urinary dysfunction in patients with multiple system atrophy. Neurourol Urodyn.
2014 Jun;33(5):516-23. 2) Yamamoto T, Sakakibara R, Uchiyama T, Yamaguchi C, Nomura
F, Ito T, Yanagisawa M, Yano M, Awa Y, Yamanishi T, Hattori T, Kuwabara S. Receiver
operating characteristic analysis of sphincter electromyography for parkinsonian syndrome.
Neurourol Urodyn. 2012 Sep;31(7):1128-34.
To read this article in full you will need to make a payment