Highlights
- •Cases with HG are more likely than controls to report 30 pre-existing conditions.
- •Cases with HG are more likely to report 57 post-pregnancy conditions.
- •Novel pre-existing issues identified include motion sickness and dental issues.
- •Significant post-pregnancy psychosocial issues include missed work (68%).
- •Physical issues were physical condition, irregular periods, and stretchmarks.
Abstract
The purpose of this study is to determine the frequency of reporting of both pre-pregnancy
and post-pregnancy psychosocial and physical issues in women with hyperemesis gravidarum
(HG). Conditions in 449 women with HG were compared to 459 unaffected women (controls).
Binary responses were analyzed using either Chi-squared or Fishers Exact test. Continuous
responses were analyzed using a t-test.
Among 60 pre-pregnancy conditions surveyed, 10 common (>5%) maternal pre-pregnancy conditions were significantly more frequently reported
by women with HG. Twenty rare (<5% controls) pre-pregnancy conditions with significantly increased reporting in the
HG group were identified. Thirty (50%) pre-pregnancy conditions were similarly reported
between cases and controls. Among 80 post-pregnancy factors surveyed, women with HG
also showed significantly higher reporting for 7 common and 50 rare post-pregnancy
outcomes. Women with HG are significantly more likely to self-report physical and
psychosocial issues both before and after pregnancy.
Keywords
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Article info
Publication history
Published online: July 20, 2016
Accepted:
July 19,
2016
Received in revised form:
July 18,
2016
Received:
April 25,
2016
Identification
Copyright
© 2016 Elsevier B.V. All rights reserved.
