- •TIND is an iatrogenic complication of aggressive glycemic control.
- •Changes in HbA1C of 1% or more per month increase the risk of TIND development.
- •Up to 10% of patients with diabetic neuropathy have symptoms due to TIND.
- •Clinical features of TIND include neuropathic pain and autonomic dysfunction.
- •Current treatments are supportive, and encourage stable glucose control.
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