Abstract
The relation between vascular sympathetic tone and the amplitude of arterial pressure
(AP) Mayer waves was examined by analyzing 60-min recordings of AP and renal sympathetic
nerve activity (RSNA) obtained in conscious rats before and after lipopolysaccharide
administration, which results in strong sympathoexcitation. Mayer waves completely
disappeared together with accompanying oscillations of RSNA. Meanwhile, the gain of
the sympathetic baroreceptor reflex was increased, thus suggesting that abolition
of Mayer waves resulted from the previously reported reduction of vascular reactivity
to α-adrenoceptor stimulation. In conclusion, the amplitude of Mayer waves cannot
be used indiscriminately as an index of vascular sympathetic tone.
Keywords
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Article info
Publication history
Published online: April 25, 2020
Accepted:
April 16,
2020
Received in revised form:
March 12,
2020
Received:
February 12,
2020
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
